Preheat the oven to 325℉. Line a baking sheet with parchment paper.
In a large bowl, use an electric mixer to combine the peanut butter, yogurt, applesauce and honey. Mix until well-blended.
Stir the flour into the wet ingredients until well-combined. You need a stiff dough, so if you need to sprinkle in a little more flour, then do it!
Flour a work surface and roll out the dough to ¼-inch thickness. Cut into dog-bone shapes, and bake for 20 minutes. Turn the biscuits over and bake for an additional 15 minutes.
Notes
Xylitol can be poisonous to your dog. Jif, Smuckers, Skippy and Peter Pan are all Xylitol-free. But the ideal peanut butter for dogs has just two ingredients: peanuts and salt. Look for the creamy natural style peanut butters. Those will be best for your dog.